| Sanchez-Valencia, Alex | Utilities Crew Chief | Utilities | 949-718-3437 | |
| Sandefur, Thomas | Assistant City Engineer | Public Works | 949-644-3321 | |
| Sanders, Laurie | Librarian I | Library - City | 949-717-3827 | |
| Sanford, Ryan | Harbor Services Worker, Lead | Harbor Department | 949-270-8159 | |
| Santibanez, Erick | Maintenance Aide | Public Works | 949-718-3463 | |
| Santoni, Micah | Lifeguard I | Fire | | |
| Santoni, Shane | Senior Pool Lifeguard | Recreation & Senior Services | | |
| Sarnowski, Allison | Department Assistant | Library - City | 949-717-3804 | |
| Schaeffer, Lauren | Recreation Coordinator, Assistant | Recreation & Senior Services | | |
| Schank, Deborah | Administrative Assistant | Community Development | 949-644-3284 | |
| Schilling, Arianna | Recreation Coordinator, Assistant | Recreation & Senior Services | | |
| Schilling, Chloe | Office Assistant | Recreation & Senior Services | 949-644-3162 | |
| Schmillen, Justin | Deputy Recreation & Senior Services Director | Recreation & Senior Services | 949-644-3160 | |
| Schoubye, Samuel | Lifeguard I | Fire | | |
| Schweitzer, Theresa | Public Works Finance/Administrative Manager | Public Works | 949-644-3335 | |
| Schwenk, Jacob | Lifeguard II | Fire | | |
| Scott, Zane | Lifeguard II | Fire | | |
| Seaton, Finley | Lifeguard I | Fire | | |
| Segura, Daniel | Utilities Specialist | Utilities | 949-718-4418 | |
| Seitz, Tyler | Lifeguard I | Fire | | |
